Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Mohsin, NU; Seebacher, W; Faist, J; Hochegger, P; Kaiser, M; Mäser, P; Belaj, F; Saf, R; Kretschmer, N; Alajlani, M; Turek, I; Brantner, A; Bauer, R; Bucar, F; Weis, R.
Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities.
Eur J Med Chem. 2018; 143(8):97-106
Doi: 10.1016/j.ejmech.2017.11.025
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PubMed
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- Co-Autor*innen der Med Uni Graz
- Kretschmer Nadine
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- Abstract:
- A series of N-benzyl tetrahydropiperidinylidene pyrrolidinium salts have been synthesized and investigated for their antiplasmodial and antitrypanosomal activities as well as for their cytotoxic effects. The antibacterial, antimycobacterial and anticancer potencies of selected compounds were examined, too. Physicochemical parameters were calculated and structure-activity-relationships are discussed. Copyright © 2017 Elsevier Masson SAS. All rights reserved.
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- Benzyl tetrahydropiperidinylidene
- ammonium salts
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