Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Moser, O; Eckstein, ML; Mueller, A; Birnbaumer, P; Aberer, F; Koehler, G; Sourij, C; Kojzar, H; Pferschy, P; Dietz, P; Bracken, RM; Hofmann, P; Sourij, H.
Pre-Exercise Blood Glucose Levels Determine the Amount of Orally Administered Carbohydrates during Physical Exercise in Individuals with Type 1 Diabetes-A Randomized Cross-Over Trial.
Nutrients. 2019; 11(6): 1287
Doi: 10.3390/nu11061287
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- Führende Autor*innen der Med Uni Graz
- Eckstein Max Lennart
- Moser Othmar
- Co-Autor*innen der Med Uni Graz
- Aberer Felix
- Köhler Gerd
- Kojzar Harald
- Pferschy Peter
- Sourij Caren
- Sourij Harald
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- Abstract:
- The aim of the study was to assess the amount of orally administered carbohydrates needed to maintain euglycemia during moderate-intensity exercise in individuals with type 1 diabetes. Nine participants with type 1 diabetes (four women, age 32.1 ± 9.0 years, BMI 25.5 ± 3.9 kg/m2, HbA1c 55 ± 7 mmol/mol (7.2 ± 0.6%)) on insulin Degludec were randomized to cycle for 55 min at moderate intensity (63 ± 7% VO2peak) for five consecutive days on either 75% or 100% of their regular basal insulin dose. The impact of pre-exercise blood glucose concentration on the carbohydrate requirement was analyzed by one-way ANOVA stratified for pre-exercise blood glucose quartiles. The effect of the basal insulin dose on the amount of orally administered carbohydrates was evaluated by Wilcoxon matched-pairs signed-rank test. The amount of orally administered carbohydrates during the continuous exercise sessions was similar for both trial arms (75% or 100% basal insulin) with median [IQR] of 36 g (9-62 g) and 36 g (9-66 g) (p = 0.78). The amount of orally administered carbohydrates was determined by pre-exercise blood glucose concentration for both trial arms (p = 0.03). Our study elucidated the importance of pre-exercise glucose concentration related orally administered carbohydrates to maintain euglycemia during exercise in individuals with type 1 diabetes.
- Find related publications in this database (Keywords)
- carbohydrates
- exercise
- type 1 diabetes
- euglycemia
- insulin