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Kay, A; Moser, C; McKhann, A; Vargas, M; Porrachia, M; Gianella, S; Hoenigl, M.
Soluble suppression of tumorigenicity 2 levels are not predictive of non-AIDS events during antiretroviral therapy-mediated viral suppression.
AIDS. 2019; 33(8):1397-1399
Doi: 10.1097/QAD.0000000000002228
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- Co-Autor*innen der Med Uni Graz
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Hönigl Martin
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- Abstract:
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: Before initiation of antiretroviral therapy (ART), levels of soluble suppression of tumorigenicity 2 (sST2) were not elevated in people living with HIV who later developed non-AIDS events (including myocardial infarction and stroke), compared with controls. However, higher sST2 levels measured pre-ART were a significant predictor of death while on ART. Future studies should explore the potential of sST2 to serve as a short-term predictor of non-AIDS events during viral suppression.
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