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SHR Neuro Krebs Kardio Lipid Stoffw Microb

Kay, A; Moser, C; McKhann, A; Vargas, M; Porrachia, M; Gianella, S; Hoenigl, M.
Soluble suppression of tumorigenicity 2 levels are not predictive of non-AIDS events during antiretroviral therapy-mediated viral suppression.
AIDS. 2019; 33(8):1397-1399 Doi: 10.1097/QAD.0000000000002228 [OPEN ACCESS]
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Co-Autor*innen der Med Uni Graz
Hönigl Martin
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Abstract:
: Before initiation of antiretroviral therapy (ART), levels of soluble suppression of tumorigenicity 2 (sST2) were not elevated in people living with HIV who later developed non-AIDS events (including myocardial infarction and stroke), compared with controls. However, higher sST2 levels measured pre-ART were a significant predictor of death while on ART. Future studies should explore the potential of sST2 to serve as a short-term predictor of non-AIDS events during viral suppression.
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Adult -
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Anti-Retroviral Agents - therapeutic use
Death -
Female -
HIV Infections - drug therapy
Humans -
Interleukin-1 Receptor-Like 1 Protein - blood
Longitudinal Studies -
Male -
Middle Aged -
Predictive Value of Tests -
Survival Analysis -
Sustained Virologic Response -
Young Adult -

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