Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Kau, T; Eicher, W; Reiterer, C; Niedermayer, M; Rabitsch, E; Senft, B; Hausegger, KA.
Dual-energy CT angiography in peripheral arterial occlusive disease-accuracy of maximum intensity projections in clinical routine and subgroup analysis.
Eur Radiol. 2011; 21(8): 1677-1686.
Doi: 10.1007/s00330-011-2099-1
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PubMed
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- Führende Autor*innen der Med Uni Graz
- Kau Thomas
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- Abstract:
- To evaluate the accuracy of dual-energy CT angiography (DE-CTA) maximum intensity projections (MIPs) in symptomatic peripheral arterial occlusive disease (PAOD). In 58 patients, DE-CTA of the lower extremities was performed on dual-source CT. In a maximum of 35 arterial segments, severity of the most stenotic lesion was graded (<10%, 10-49% and 50-99% luminal narrowing or occlusion) independently by two radiologists, with DSA serving as the reference standard. In DSA, 52.3% of segments were significantly stenosed or occluded. Agreement of DE-CTA MIPs with DSA was good in the aorto-iliac and femoro-popliteal regions (κ = 0.72; κ = 0.66), moderate in the crural region (κ = 0.55), slight in pedal arteries (κ = 0.10) and very good in bypass segments (κ = 0.81). Accuracy was 88%, 78%, 74%, 55% and 82% for the respective territories and moderate (75%) overall, with good sensitivity (84%) and moderate specificity (67%). Sensitivity and specificity was 82% and 76% in claudicants and 84% and 61% in patients with critical limb ischaemia. While correlating well with DSA above the knee, accuracy of DE-CTA MIPs appeared to be moderate in the calf and largely insufficient in calcified pedal arteries, especially in patients with critical limb ischaemia.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Aged, 80 and over -
- Angiography - methods
- Angiography, Digital Subtraction -
- Arterial Occlusive Diseases - diagnostic imaging
- Female -
- Humans -
- Leg - blood supply
- Leg - diagnostic imaging
- Male -
- Middle Aged -
- Peripheral Vascular Diseases - diagnostic imaging
- Radiographic Image Interpretation, Computer-Assisted -
- Sensitivity and Specificity -
- Severity of Illness Index -
- Statistics, Nonparametric -
- Tomography, X-Ray Computed - methods
- Find related publications in this database (Keywords)
- Computed tomography and angiography
- Dual energy CT
- Peripheral arterial occlusive disease
- Critical limb ischemia
- Lower extremities