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Bousquet, J; Pfaar, O; Togias, A; Schünemann, HJ; Ansotegui, I; Papadopoulos, NG; Tsiligianni, I; Agache, I; Anto, JM; Bachert, C; Bedbrook, A; Bergmann, KC; Bosnic-Anticevich, S; Bosse, I; Brozek, J; Calderon, MA; Canonica, GW; Caraballo, L; Cardona, V; Casale, T; Cecchi, L; Chu, D; Costa, E; Cruz, AA; Czarlewski, W; Durham, SR; Du, Toit, G; Dykewicz, M; Ebisawa, M; Fauquert, JL; Fernandez-Rivas, M; Fokkens, WJ; Fonseca, J; Fontaine, JF; Gerth, van, Wijk, R; Haahtela, T; Halken, S; Hellings, PW; Ierodiakonou, D; Iinuma, T; Ivancevich, JC; Jacobsen, L; Jutel, M; Kaidashev, I; Khaitov, M; Kalayci, O; Kleine, Tebbe, J; Klimek, L; Kowalski, ML; Kuna, P; Kvedariene, V; La, Grutta, S; Larenas-Linemann, D; Lau, S; Laune, D; Le, L; Lodrup, Carlsen, K; Lourenço, O; Malling, HJ; Marien, G; Menditto, E; Mercier, G; Mullol, J; Muraro, A; O'Hehir, R; Okamoto, Y; Pajno, GB; Park, HS; Panzner, P; Passalacqua, G; Pham-Thi, N; Roberts, G; Pawankar, R; Rolland, C; Rosario, N; Ryan, D; Samolinski, B; Sanchez-Borges, M; Scadding, G; Shamji, MH; Sheikh, A; Sturm, GJ; Todo, Bom, A; Toppila-Salmi, S; Valentin-Rostan, M; Valiulis, A; Valovirta, E; Ventura, MT; Wahn, U; Walker, S; Wallace, D; Waserman, S; Yorgancioglu, A; Zuberbier, T, , ARIA, Working, Group.
2019 ARIA Care pathways for allergen immunotherapy.
Allergy. 2019; 74(11):2087-2102 Doi: 10.1111/all.13805 [OPEN ACCESS]
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Co-Autor*innen der Med Uni Graz
Sturm Gunter
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Abstract:
Allergen immunotherapy (AIT) is a proven therapeutic option for the treatment of allergic rhinitis and/or asthma. Many guidelines or national practice guidelines have been produced but the evidence-based method varies, many are complex and none propose care pathways. This paper reviews care pathways for AIT using strict criteria and provides simple recommendations that can be used by all stakeholders including healthcare professionals. The decision to prescribe AIT for the patient should be individualized and based on the relevance of the allergens, the persistence of symptoms despite appropriate medications according to guidelines as well as the availability of good-quality and efficacious extracts. Allergen extracts cannot be regarded as generics. Immunotherapy is selected by specialists for stratified patients. There are no currently available validated biomarkers that can predict AIT success. In adolescents and adults, AIT should be reserved for patients with moderate/severe rhinitis or for those with moderate asthma who, despite appropriate pharmacotherapy and adherence, continue to exhibit exacerbations that appear to be related to allergen exposure, except in some specific cases. Immunotherapy may be even more advantageous in patients with multimorbidity. In children, AIT may prevent asthma onset in patients with rhinitis. mHealth tools are promising for the stratification and follow-up of patients.
Find related publications in this database (using NLM MeSH Indexing)
Allergens - administration & dosage, immunology
Animals - administration & dosage
Asthma - epidemiology, immunology, therapy
Attitude of Health Personnel - administration & dosage
Biomarkers - administration & dosage
Clinical Decision-Making - administration & dosage
Comorbidity - administration & dosage
Cost of Illness - administration & dosage
Cost-Benefit Analysis - administration & dosage
Critical Pathways - administration & dosage
Desensitization, Immunologic - adverse effects, methods
Disease Management - administration & dosage
Disease Susceptibility - administration & dosage
Humans - administration & dosage
Practice Guidelines as Topic - administration & dosage
Precision Medicine - methods
Rhinitis, Allergic - epidemiology, immunology, therapy
Treatment Outcome - administration & dosage

Find related publications in this database (Keywords)
allergen immunotherapy
asthma
children
mHealth
rhinitis
stratification
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