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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Schrem, H; Till, N; Becker, T; Bektas, H; Manns, MP; Strassburg, CP; Klempnauer, J.
[Long-term results after liver transplantation].
Chirurg. 2008; 79(2): 121-129.
Doi: 10.1007/s00104-007-1457-7
Web of Science
PubMed
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- Leading authors Med Uni Graz
- Schrem Harald Heinrich
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- Abstract:
- Liver transplantation has been reported to reach excellent results for selected indications. We analysed the results of liver transplantation in our centre over a period of 23 years, with a total of 2,114 consecutive liver transplants in 1,773 patients (eras I-III 5.5 years each, era IV 6.5 years). Overall 20-year survival after liver transplantation was 29.8%. The most frequent leading causes of death were infections of various origins (30%), tumour recurrence (14.2%), and pneumonia (8.4%). The most frequent leading causes for graft loss were infection of various origins (19.6%), initial nonfunction of the graft (14.6%), and tumour recurrence (9.6%). Both long-term patient and graft survival were significantly better after primary liver transplantation than after first retransplantation (P<0.001). Patient and graft long-term survival improved significantly across all four consecutive eras (P<0.001). In era IV, the most recent, 5-year patient survival reached 96% for PBC, 89.4% for PSC, 78.5% for biliary atresia, 70% for acute liver failure, 69.1% for HBV-related cirrhosis, 61.3% for hepatocellular carcinoma, and 56% for HCV-related cirrhosis.
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- Adolescent -
- Adult -
- Aged -
- Cause of Death -
- Child -
- Child, Preschool -
- Diffusion of Innovation -
- Female -
- Follow-Up Studies -
- Follow-Up Studies -
- Graft Survival -
- Humans -
- Infant -
- Liver Failure - mortality
- Liver Failure - surgery
- Liver Neoplasms - mortality
- Liver Neoplasms - surgery
- Liver Transplantation -
- Male -
- Middle Aged -
- Postoperative Complications - etiology
- Postoperative Complications - mortality
- Postoperative Complications - surgery
- Prognosis -
- Reoperation -
- Retrospective Studies -
- Survival Rate -
- Systemic Inflammatory Response Syndrome - etiology
- Systemic Inflammatory Response Syndrome - mortality
- Find related publications in this database (Keywords)
- liver transplantation
- long-term results
- causes of death
- liver transplant loss
- liver transplant survival
- tumor recurrence
- liver cirrhosis