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Greimel, E; Bjelic-Radisic, V; Nagele, E; Bliem, B; Tamussino, K.
Quality of life in patients with ovarian cancer
ONKOLOGE. 2019; 25(2): 151-156.
Doi: 10.1007/s00761-018-0484-y
Web of Science
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- Leading authors Med Uni Graz
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Greimel Elfriede Renate
- Co-authors Med Uni Graz
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Bjelic-Radisic Vesna
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Bliem Brigitte
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Nagele Eva Helene
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Tamussino Karl
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- Abstract:
- Progress in surgical and systemic treatment for ovarian cancer has prolonged survival times of patients and changed the focus towards patients' quality of life (QoL). The inclusion of patient-reported outcomes (PROs) as primary or secondary outcomes in clinical ovarian cancer studies has significantly increased in recent years. There are standardized instruments developed specifically for ovarian cancer patients to measure PROs. Web-based ePRO questionnaires are also available, saving time and expense. Results from clinical studies with PROs as the focus have led to a change in the international standardized therapy for ovarian cancer. Based on these data carboplatin/paclitaxel has become the new worldwide standard primary therapy for advanced ovarian cancer. A further individualization of treatment taking QoL of patients into account, could be made possible for late relapsed ovarian cancer. In addition to clinical trials, PROs are increasingly being used in routine clinical practice. The majority of cancer patients support the routine assessment of QoL. The PRO data provide important information about the subjective effect of the disease and the treatment on the QoL of patients. This information can then be used for clinical decision-making to select the best treatment option based on the needs of the patients.
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