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SHR Neuro Cancer Cardio Lipid Metab Microb
Brunner, R; Kurz, A; Adelsmayr, G; Holzinger, U.
Basal glucosuria is ubiquitous in critically ill patients.
Nephrology (Carlton). 2015; 20(4): 293-296.
Doi: 10.1111/nep.12377
Web of Science
PubMed
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- Co-authors Med Uni Graz
- Adelsmayr Gabriel
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- Abstract:
- The 'renal threshold for glucose' has never been evaluated in critically ill patients. Therefore, we aimed to investigate the renal glucose threshold in this patient group using high-sensitivity urine glucose assays. In this retrospective analysis of prospectively collected data, we analysed 100 consecutive critically ill patients from a medical intensive care unit (ICU). Arterial blood glucose and spot urine glucose were simultaneously quantified daily during the first week after ICU admission. Three hundred seventy-three pairs of blood/urine glucose were plotted in five pre-defined categories of blood glucose (<80, 80-109, 110-139, 140-179 and ≥180 mg/dL). Urine glucose values of the five categories were compared using the Kruskal-Wallis test to assess the relation with blood glucose. Urine glucose was detected in virtually all of the urine samples. Urine glucose showed a positive nonlinear correlation with blood glucose and was significantly elevated at blood glucose levels of 140-179 and ≥180 mg/dL compared with lower blood glucose ranges. Basal glucosuria is ubiquitous in critically ill patients. A 'soft' renal threshold for glucose is present at blood glucose levels in the range of 140-179 mg/dL. © 2015 Asian Pacific Society of Nephrology.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Biomarkers - blood
- Biomarkers - urine
- Blood Glucose - analysis
- Critical Illness -
- Female -
- Glucose - analysis
- Glycosuria - blood
- Glycosuria - diagnosis
- Glycosuria - urine
- Humans -
- Intensive Care Units -
- Male -
- Middle Aged -
- Nonlinear Dynamics -
- Predictive Value of Tests -
- Retrospective Studies -
- Up-Regulation -
- Urinalysis -
- Find related publications in this database (Keywords)
- critical care
- glucose
- intensive care
- kidney
- renal glucosuria