Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Bugger, H; Bode, C.
The vulnerable myocardium. Diabetic cardiomyopathy.
Hamostaseologie. 2015; 35(1): 17-24.
Doi: 10.5482/HAMO-14-09-0038
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Bugger Heiko Matthias
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Cardiovascular disease is the major cause of morbidity and mortality in subjects suffering from diabetes mellitus. While coronary artery disease is the leading cause of cardiac complications in diabetics, it is widely recognized that diabetes increases the risk for the development of heart failure independently of coronary heart disease and hypertension. This increased susceptibility of the diabetic heart to develop structural and functional impairment is termed diabetic cardiomyopathy. The number of different mechanisms proposed to contribute to diabetic cardiomyopathy is steadily increasing and underlines the complexity of this cardiac entity. In this review the mechanisms that account for the increased myocardial vulnerability in diabetic cardiomyopathy are discussed.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Cytokines - metabolism
- Diabetic Cardiomyopathies - complications
- Diabetic Cardiomyopathies - physiopathology
- Heart - physiopathology
- Humans -
- Models, Cardiovascular -
- Oxidative Stress -
- Reactive Oxygen Species - metabolism
- Ventricular Dysfunction, Left - etiology
- Ventricular Dysfunction, Left - physiopathology
- Find related publications in this database (Keywords)
- Diabetes
- cardiomyopathy
- energy metabolism
- mitochondria