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SHR Neuro Cancer Cardio Lipid Metab Microb

Fingerhut, A; Tzu-Liang Chen, W; Boni, L; Uranues, S.
Complete mesocolic excision for colonic cancer.
Minerva Chir. 2019; 74(2): 148-159. Doi: 10.23736/S0026-4733.18.07777-5
Web of Science PubMed FullText FullText_MUG

Co-authors Med Uni Graz: Uranüs Selman
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Abstract:: Complete mesocolic excision for colonic cancer is similar in concept to total mesorectal excision for rectal cancer. This review aims to provide the embryological and anatomical rationale behind CME, and to review the current literature on CME, relative to the feasibility via laparoscopy, the oncological adequacy and outcomes. A literature search was performed at the end of 2017 according the PRISMA guidelines for systematic reviews. Of 3980 articles found, we analyzed 96 articles. Of note, many case series had overlapping populations; there were five review articles, two consensus conference proceedings, six comparative but only one randomized trial. The embryonic and anatomical rationale is well described. CME is feasible via laparoscopy, which may facilitate dissection and anatomic precision: no statistically significant differences were found when compared to open CME regarding overall survival. However, morbidity may be higher in the hands of non-expert laparoscopic surgeons. Oncological adequacy can be obtained with laparoscopic CME, with increased lymph node retrieval. However, until now, there is no formal proof that CME improves local recurrence or survival.
Find related publications in this database (Keywords): Laparoscopy; Colonic neoplasms; Embryology; Consensus