Medizinische Universität Graz - Research portal
Selected Publication:
Offenbacher, H; Fazekas, F; Schmidt, R; Kleinert, R; Payer, F; Kleinert, G; Lechner, H.
MRI in tuberculous meningoencephalitis: report of four cases and review of the neuroimaging literature.
J Neurol. 1991; 238(6):340-344
Doi: 10.1007/BF00315335
(- Case Report)
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- Co-authors Med Uni Graz
- Fazekas Franz
- Kleinert Gertrude
- Kleinert Reinhold
- Payer Franz
- Schmidt Reinhold
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- Abstract:
- The contribution of MRI is reported in four adult patients with tuberculous meningoencephalitis (TbM) and with autopsy correlation in one. Contrast-enhanced T1-weighted MRI revealed the characteristic basal meningeal inflammation of TbM and its focal spreading into adjacent brain. Mixed and T2-weighted pulse sequences delineated a plethora of parenchymal abnormalities. Their relation to TbM was established by a close matching of the patient's neurological findings, contrast enhancement or a change in lesion size. The latter accurately reflected the clinical course in all patients. It remained difficult, however, to distinguish between ischaemic and inflammatory changes, which in some locations were intermixed even histologically. From our experience and that of other groups, MRI provides more diagnostic information in TbM than CT. Moreover, MRI promises to be a useful tool for monitoring treatment response.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Contrast Media -
- Female -
- Gadolinium DTPA -
- Humans -
- Image Enhancement - methods
- Magnetic Resonance Imaging - methods
- Male - methods
- Meningoencephalitis - diagnosis
- Middle Aged - diagnosis
- Organometallic Compounds - diagnostic use
- Pentetic Acid - diagnostic use
- Tomography, X-Ray Computed - diagnostic use
- Tuberculosis, Meningeal - diagnosis
- Find related publications in this database (Keywords)
- Tuberculous Meningitis
- Magnetic Resonance Imaging
- Computed Tomography