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SHR Neuro Cancer Cardio Lipid Metab Microb

Zhou, Q; Zirlik, A; Willecke, F.
Cardiovascular disease in diabetes. Modulation of inflammatory response as a new treatment option
DIABETOLOGE. 2018; 14(6): 393-403. Doi: 10.1007/s11428-018-0365-4 [OPEN ACCESS]
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Leading authors Med Uni Graz
Zirlik Andreas
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Abstract:
Over the past decade, alarge number of scientific publications have identified inflammation as amajor causal factor in diabetes mellitus and atherosclerosis. Compared to nondiabetic patients, activation of inflammatory cytokines and cells are increased in patients with diabetes. This is partly caused by hyperglycemia and insulin resistance/deficiency.In this review, the key factors of diabetes-associated inflammation are described and potential anti-inflammatory therapies that could potentially reduce the risk of diabetic macroangiopathy are discussed.The multifactorial therapy of diabetes mellitus consisting of blood sugar, cholesterol and high blood pressure control could be supplemented by anti-inflammatory therapies in the future.

Find related publications in this database (Keywords)
Glucose metabolism disorders
Diabetic complications
Cardiovascular system
Atherosclerosis
Anti-inflammatory agents
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