Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
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Schäfer, VS; Chrysidis, S; Dejaco, C; Duftner, C; Iagnocco, A; Bruyn, GA; Carrara, G; D'Agostino, MA; De Miguel, E; Diamantopoulos, AP; Fredberg, U; Hartung, W; Hocevar, A; Juche, A; Kermani, TA; Koster, MJ; Lorenzen, T; Macchioni, P; Milchert, M; Døhn, UM; Mukhtyar, C; Ponte, C; Ramiro, S; Scirè, CA; Terslev, L; Warrington, KJ; Dasgupta, B; Schmidt, WA.
Assessing Vasculitis in Giant Cell Arteritis by Ultrasound: Results of OMERACT Patient-based Reliability Exercises.
J Rheumatol. 2018; 45(9):1289-1295
Doi: 10.3899/jrheum.171428
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Dejaco Christian
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- Abstract:
- To test the reliability of Outcome Measures in Rheumatology Clinical Trials (OMERACT) consensus-based ultrasound definitions for normal and vasculitic temporal and axillary arteries in patients with giant cell arteritis (GCA) and in controls. A preliminary 1-day meeting and a full 3-day meeting fulfilling OMERACT Ultrasound Group guidelines were held. Temporal and axillary arteries were examined at 2 timepoints by 12 sonographers on 4 patients with GCA and 2 controls. The aim was to test inter- and intrareader reliability for normal findings, halo sign, and compression sign. In both meetings, patients had established GCA. Pathology was more recent in the full meeting, which was preceded by 6 h of training. Scanning time was 15-20 min instead of 10-13 min. In the preliminary exercise, interreader reliabilities were fair to moderate for the overall diagnosis of GCA (Light κ 0.29-0.51), and poor to fair for identifying vasculitis in the respective anatomical segments (Light κ 0.02-0.46). Intrareader reliabilities were moderate (Cohen κ 0.32-0.64). In the main exercise, interreader reliability was good to excellent (Light κ 0.76-0.86) for the overall diagnosis of GCA, and moderate to good (Light κ 0.46-0.71) for identifying vasculitis in the respective anatomical segments. Intrareader reliability was excellent for diagnosis of GCA (Cohen κ 0.91) and good (Cohen κ 0.71-0.80) for the anatomical segments. OMERACT-derived definitions of halo and compression signs of temporal and axillary arteries are reliable in recent-onset GCA if experienced sonographers (> 300 examinations) have 15-20 min for a standardized examination with prior training and apply > 15 MHz probes.
- Find related publications in this database (Keywords)
- GIANT CELL ARTERITIS
- ULTRASOUND
- RELIABILITY
- DIAGNOSIS
- VASCULITIS