Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Halkett, GKB; Wigley, CA; Aoun, SM; Portaluri, M; Tramacere, F; Livi, L; Detti, B; Arcangeli, S; Lund, JA; Kristensen, A; McFadden, N; Grun, A; Bydder, S; Sackerer, I; Greimel, E; Spry, N; EORTC Quality of Life Group.
International validation of the EORTC QLQ-PRT20 module for assessment of quality of life symptoms relating to radiation proctitis: a phase IV study.
Radiat Oncol. 2018; 13(1):162-162
Doi: 10.1186/s13014-018-1107-x
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- Co-Autor*innen der Med Uni Graz
- Greimel Elfriede Renate
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- Abstract:
- Although patients experience radiation proctitis post radiotherapy no internationally tested instruments exist to measure these symptoms. This Phase IV study tested the scale structure, reliability and validity and cross-cultural applicability of the EORTC proctitis module (QLQ-PRT23) in patients who were receiving pelvic radiotherapy. Patients (n = 358) from six countries completed the EORTC QLQ-C30, QLQ-PRT23 and EORTC Quality of Life Group debriefing questions. Clinicians completed the EORTC Radiation Therapy Oncology Group scale. Questionnaires were completed at four time-points. The module's scale structure was examined and validated using standard psychometric analysis techniques. Three items were dropped from the module (QLQ-PRT23 → QLQ-PRT20). Factor analysis identified five factors in the module: bowel control; bloating and gas; emotional function/lifestyle; pain; and leakage. Inter-item correlations were within r = 0.3-0.7. Test-Retest reliability was high. All multi-item scales discriminated between patients showing symptoms and those without symptomology. The module discriminated symptoms from the clinician completed scoring and for age, gender and comorbidities. The EORTC QLQ-PRT20 is designed to be used in addition to the EORTC QLQ-C30 to measure quality of life in patients who receive pelvic radiotherapy. The EORTC QLQ-PRT20 is quick to complete, acceptable to patients, has good content validity and high reliability. Australian and New Zealand Clinical Trials Registry (ANZCTR) ACTRN12609000972224 .
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Aged, 80 and over -
- Aged, 80 and over -
- Cross-Cultural Comparison -
- Factor Analysis, Statistical -
- Female -
- Health Care Surveys -
- Humans -
- Male -
- Middle Aged -
- Proctitis - diagnosis
- Proctitis - etiology
- Psychometrics -
- Quality of Life -
- Radiation Injuries - complications
- Reproducibility of Results -
- Symptom Assessment - methods