Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Steinke, S; Zeidler, C; Riepe, C; Bruland, P; Soto-Rey, I; Storck, M; Augustin, M; Bobko, S; Garcovich, S; Legat, FJ; Lvov, A; Misery, L; Osada, N; Reich, A; Şavk, E; Serra-Baldrich, E; Streit, M; Szepietowski, JC; Weger, W; Dugas, M; Ständer, S.
Humanistic burden of chronic pruritus in patients with inflammatory dermatoses: Results of the European Academy of Dermatology and Venereology Network on Assessment of Severity and Burden of Pruritus (PruNet) cross-sectional trial.
J Am Acad Dermatol. 2018; 79(3):457-463
Doi: 10.1016/j.jaad.2018.04.044
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Legat Franz
- Weger Wolfgang
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- Abstract:
- Chronic pruritus is a multifactorial, challenging symptom of global relevance. The European Academy of Dermatology and Venereology Network on Assessment of Severity and Burden of Pruritus (PruNet) investigation aimed to analyze the severity and humanistic burden of chronic pruritus in patients suffering from inflammatory dermatoses across Europe. Prospectively collected routine data on 552 patients (with atopic dermatitis, contact dermatitis, prurigo nodularis, psoriasis vulgaris, lichen planus, or mycosis fungoides [pruritus numeric rating scale score ≥3]) from 9 European centers (in Austria, France, Germany, Italy, Poland, Russia, Spain, Switzerland, and Turkey) were analyzed by univariate and multivariate variance analyses of various itch characteristics and quality of life (as measured by the Dermatology Life Quality Index and the ItchyQoL). Duration, frequency, and intensity of pruritus (according to a numeric rating scale and visual analog scale) and related impairment of quality of life differed between European centers and dermatologic diagnoses (P < .05). The country in which the center was located had a greater impact on how patients evaluated pruritus intensity and quality of life than diagnosis did (P < .001). One center per country was included. The humanistic burden of chronic pruritus in patients with inflammatory dermatoses is high. European cross-cultural factors may have a stronger influence than a specific dermatologic diagnosis on how patients rate intensity of pruritus and quality of life. Copyright © 2018 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Chronic Disease -
- Cost of Illness -
- Cross-Sectional Studies -
- Dermatitis, Atopic - complications
- Dermatitis, Contact - complications
- Dermatitis, Contact -
- Female -
- Humans -
- Lichen Planus - complications
- Male -
- Middle Aged -
- Mycosis Fungoides - complications
- Prurigo - complications
- Pruritus - etiology
- Psoriasis - complications
- Quality of Life -
- Severity of Illness Index -
- Find related publications in this database (Keywords)
- care situation
- humanistic burden
- pruritus intensity
- pruritus measurement
- prurigo
- quality of life