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Grübler, MR; Wigger, O; Berger, D; Blöchlinger, S.
Basic concepts of heart-lung interactions during mechanical ventilation.
Swiss Med Wkly. 2017; 147(5):w14491-w14491 Doi: 10.4414/smw.2017.14491 [OPEN ACCESS]
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Führende Autor*innen der Med Uni Graz
Grübler Martin
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Abstract:
Critically ill patients with the need for mechanical ventilation show complex interactions between respiratory and cardiovascular physiology. These interactions are important as they may guide the clinician's therapeutic decisions and, possibly, affect patient outcome. The aim of the present review is to provide the practicing physician with an overview of the concepts of heart-lung interactions during mechanical ventilation. We outline the basic cardiac and respiratory physiology during spontaneous breathing and under mechanical ventilation. The main focus is on the interaction between positive pressure ventilation and its effects on right and left ventricular pre- and afterload and ventricular interdependence. Further we discuss different modalities to assess volume responsiveness, such as pulse pressure variation. We aim to familiarise the reader with cardiovascular side effects of mechanical ventilation when experiencing weaning problems or right heart failure.
Find related publications in this database (using NLM MeSH Indexing)
Blood Pressure - physiology
Cardiovascular System - physiopathology
Heart - physiopathology
Heart Rate -
Hemodynamics -
Humans -
Lung - physiopathology
Respiration, Artificial - adverse effects
Respiration, Artificial - instrumentation
Respiration, Artificial - methods

Find related publications in this database (Keywords)
heart-lung interactions
ventricular function
myocardial function
mechanical ventilation
positive end-expiratory pressure
right atrial pressure
cardiac output
right-heart failure
venous return
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