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Szepfalusi, Z; Horak, F; Eiwegger, T; Horak, E; Huttegger, I; Wolf-Abdolvahab, S; Varga, EM; Riedler, J.
Abridged version of allergen-specific immunotherapy for IgE-mediated diseases in childhood and adolescence. Overview of approved allergen products in AustriaUpdate 2017
MONATSSCHR KINDERH. 2018; 166(6): 521-528. Doi: 10.1007/s00112-018-0478-2 [OPEN ACCESS]
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Co-Autor*innen der Med Uni Graz
Varga Eva-Maria
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Abstract:
The consensus report from 2009 on allergen-specific immunotherapy for immunoglobulin E (IgE) mediated allergic diseases in childhood and adolescence was issued due to the increasingly large offer of allergen preparations and the heterogeneous state of studies. The field of immunotherapy has now undergone a clear restructuring (regulations of the European Union [EU], therapy allergen regulations etc.). There remains the ethical obligation to treat children and adolescents with allergen preparations, which were also tested in studies including children and adolescents and were classified as being effective and safe (EU regulative, European Medicines Agency [EMA]). The updated list of immunotherapy preparations from 2017 with particular reference to children and adolescents valid for Austria has now been adapted. A critical reappraisal of the study situation has been carried out. Some immunotherapy products which have recently come onto the market show an improved dataset from studies that were carried out exclusively on children and adolescents. These approved and licensed products can therefore be recommended for indication-compliant administration to children and adolescents.

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