Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Ahammer, H; Scheruebel, S; Arnold, R; Mayrhofer-Reinhartshuber, M; Lang, P; Dolgos, Á; Pelzmann, B; Zorn-Pauly, K.
Sinoatrial Beat to Beat Variability Assessed by Contraction Strength in Addition to the Interbeat Interval.
Front Physiol. 2018; 9:546-546
Doi: 10.3389/fphys.2018.00546
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Ahammer Helmut
- Scherübel-Posch Susanne
- Co-Autor*innen der Med Uni Graz
- Arnold Robert
- Lang Petra
- Pelzmann Brigitte
- Zorn-Pauly Klaus
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Beat to beat variability of cardiac tissue or isolated cells is frequently investigated by determining time intervals from electrode measurements in order to compute scale dependent or scale independent parameters. In this study, we utilize high-speed video camera recordings to investigate the variability of intervals as well as mechanical contraction strengths and relative contraction strengths with nonlinear analyses. Additionally, the video setup allowed us simultaneous electrode registrations of extracellular potentials. Sinoatrial node tissue under control and acetylcholine treated conditions was used to perform variability analyses by computing sample entropies and Higuchi dimensions. Beat to beat interval variabilities measured by the two recording techniques correlated very well, and therefore, validated the video analyses for this purpose. Acetylcholine treatment induced a reduction of beating rate and contraction strength, but the impact on interval variability was negligible. Nevertheless, the variability analyses of contraction strengths revealed significant differences in sample entropies and Higuchi dimensions between control and acetylcholine treated tissue. Therefore, the proposed high-speed video camera technique might represent a non-invasive tool that allows long-lasting recordings for detecting variations in beating behavior over a large range of scales.
- Find related publications in this database (Keywords)
- heart rate variability
- beat to beat variability
- video motion analysis
- sinoatrial node
- acetylcholine
- sample entropy
- Higuchi dimension