Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Gallasch, E; Rafolt, D; Postruznik, M; Fresnoza, S; Christova, M.
Decrease of motor cortex excitability following exposure to a 20 Hz magnetic field as generated by a rotating permanent magnet.
Clin Neurophysiol. 2018; 129(7):1397-1402
Doi: 10.1016/j.clinph.2018.03.045
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Gallasch Eugen
- Co-authors Med Uni Graz
- Christova Monica
- Postruznik Magdalena
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- OBJECTIVES: Rotation of a static magnet over the motor cortex (MC) generates a transcranial alternating magnetic field (tAMF), and a linked alternating electrical field. The aim of this transcranial magnetic stimulation (TMS) study is to investigate whether such fields are able to influence MC excitability, and whether there are parallels to tACS induced effects. METHODS: Fourteen healthy volunteers received 20 Hz tAMF stimulation over the MC, over the vertex, and 20 Hz tACS over the MC, each with a duration of 15 min. TMS assessments were performed before and after the interventions. Changes in motor evoked potentials (MEP), short interval intra-cortical inhibition (SICI) and intra-cortical facilitation (ICF) were evaluated. RESULTS: The tACS and the tAMF stimulation over the MC affected cortical excitability in a different way. After tAMF stimulation MEP amplitudes and ICF decreased and the effect of SICI increased. After tACS MEP amplitudes increased and there were no effects on SICI and ICF. CONCLUSIONS: The recorded single and paired pulse MEPs indicate a general decrease of MC excitability following 15 min of tAMF stimulation. SIGNIFICANCE: The effects demonstrate that devices based on rotating magnets are potentially suited to become a novel brain stimulation tool in clinical neurophysiology.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult - administration & dosage
- Cross-Over Studies - administration & dosage
- Electromyography - methods
- Evoked Potentials, Motor - physiology
- Female - administration & dosage
- Humans - administration & dosage
- Magnetic Fields - administration & dosage
- Magnets - administration & dosage
- Male - administration & dosage
- Motor Cortex - physiology
- Single-Blind Method - administration & dosage
- Transcranial Magnetic Stimulation - instrumentation, methods
- Find related publications in this database (Keywords)
- TMS
- tACS
- Motor cortex
- Electromagnetic induction
- Noninvasive brain stimulation
- Modulation of cortical excitability