Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Baum, T; Sauerschnig, M; Penzel, J; Jungmann, PM; Waldt, S; Rummeny, EJ; Wörtler, K; Bauer, JS.
Early changes of trabecular bone structure in asymptomatic subjects with knee malalignment.
J Comput Assist Tomogr. 2014; 38(1): 137-141.
Doi: 10.1097/RCT.0b013e3182a90f08
Web of Science
PubMed
FullText
FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Sauerschnig Martin
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- To investigate whether alterations of trabecular bone structure can already be found in young asymptomatic subjects with knee malalignment. Forty-eight subjects with neutral, mild varus, severe varus, and valgus knee joint alignment were included in this study (12 subjects in each group). Histomorphometric and texture parameters of the trabecular bone in the medial/lateral femur/tibia were determined using 1.5-T magnetic resonance imaging. Apparent trabecular thickness in the medial tibia compartment was lower in the valgus group (mean ± standard error, 0.353 ± 0.012 mm) compared with the neutral (0.396 ± 0.011 mm; P = 0.043), mild varus (0.403 ± 0.011 mm; P = 0.038) and severe varus groups (0.416 ± 0.013 mm; P = 0.015). In the medial femur compartment, fractal dimension was significantly greater in the mild (1.697 ± 0.005; P = 0.015) and severe varus groups (1.698 ± 0.005; P = 0.036) than in the valgus group (1.674 ± 0.005). The observed findings may be signs of the adaptation of the subchondral bone to altered loading conditions and possibly of early knee joint impairment.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Bone Malalignment - pathology
- Female -
- Femur - pathology
- Humans -
- Image Interpretation, Computer-Assisted -
- Magnetic Resonance Imaging - methods
- Male -
- Osteoarthritis, Knee - pathology
- Reproducibility of Results -
- Tibia - pathology
- Find related publications in this database (Keywords)
- MRI
- knee malalignment
- trabecular bone structure
- osteoarthritis