Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Haberl, J; Zollner, G; Fickert, P; Stadlbauer, V.
To salt or not to salt?-That is the question in cirrhosis.
Liver Int. 2018; 38(7):1148-1159
Doi: 10.1111/liv.13750
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- Führende Autor*innen der Med Uni Graz
- Stadlbauer-Köllner Vanessa
- Traub Julia
- Co-Autor*innen der Med Uni Graz
- Fickert Peter
- Zollner Gernot
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- Abstract:
- Ascites is the most common complication of patients with cirrhosis, resulting from portal hypertension and vasodilatation. It is associated with an increased risk for the development of hyponatraemia and renal failure and has a high mortality rate of 20% per year. The development of ascites represents a baleful sign in the course of disease in cirrhosis. To prevent complications of cirrhosis and improve quality of life, an effective management of ascites is pivotal. Combined salt restriction and diuretic therapy is recommended as first-line therapy in numerous clinical practice guidelines. In contrast, there has been a debate on whether a strict salt-restricted diet for cirrhosis patients should be used at all since salt restriction may increase the risk for malnutrition which in turn may negatively impact on quality of life and survival. This review aims to summarize the current pros and cons regarding salt restriction in patients with cirrhosis and proposes the importance of achieving a sodium balance throughout different stages of cirrhosis. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
- Find related publications in this database (using NLM MeSH Indexing)
- Ascites - etiology
- Ascites - therapy
- Diet, Sodium-Restricted - adverse effects
- Diuretics - therapeutic use
- Humans -
- Hypertension, Portal - complications
- Liver Cirrhosis - complications
- Practice Guidelines as Topic -
- Quality of Life -
- Randomized Controlled Trials as Topic -
- Sodium - blood
- Water-Electrolyte Imbalance - blood
- Water-Electrolyte Imbalance - diet therapy
- Find related publications in this database (Keywords)
- ascites
- cirrhosis
- diuretics
- salt intake
- sodium balance