Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Galler, H; Feierl, G; Petternel, C; Reinthaler, FF; Haas, D; Habib, J; Kittinger, C; Luxner, J; Zarfel, G.
Multiresistant Bacteria Isolated from Activated Sludge in Austria.
Int J Environ Res Public Health. 2018; 15(3):
Doi: 10.3390/ijerph15030479
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Galler Herbert
- Zarfel Gernot
- Co-authors Med Uni Graz
- Feierl Gebhard
- Haas Doris
- Habib Juliana-Salwa-Monir
- Kittinger Clemens
- Luxner Josefa
- Petternel Christian
- Reinthaler Franz
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Wastewater contains different kinds of contaminants, including antibiotics and bacterial isolates with human-generated antibiotic resistances. In industrialized countries most of the wastewater is processed in wastewater treatment plants which do not only include commercial wastewater, but also wastewater from hospitals. Three multiresistant pathogens-extended spectrum β-lactamase (ESBL)-harbouring Enterobacteriaceae (Gram negative bacilli), methicillin resistantStaphylococcus aureus(MRSA) and vancomycin resistant Enterococci (VRE)-were chosen for screening in a state of the art wastewater treatment plant in Austria. Over an investigation period of six months all three multiresistant pathogens could be isolated from activated sludge. ESBL was the most common resistance mechanism, which was found in different species of Enterobacteriaceae, and in oneAeromonasspp. Sequencing of ESBL genes revealed the dominance of genes encoding members of CTX-M β-lactamases family and a gene encoding for PER-1 ESBL was detected for the first time in Austria. MRSA and VRE could be isolated sporadically, including one EMRSA-15 isolate. Whereas ESBL is well documented as a surface water contaminant, reports of MRSA and VRE are rare. The results of this study show that these three multiresistant phenotypes were present in activated sludge, as well as species and genes which were not reported before in the region. The ESBL-harbouring Gram negative bacilli were most common.
- Find related publications in this database (Keywords)
- ESBL
- MRSA
- VRE
- sewage sludge
- PER-1