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SHR Neuro Cancer Cardio Lipid Metab Microb

Prattes, J; Hoenigl, M; Zinke, SE; Heldt, S; Eigl, S; Johnson, GL; Bustin, S; Stelzl, E; Kessler, HH.
Evaluation of the new AspID polymerase chain reaction assay for detection of Aspergillus species: A pilot study.
Mycoses. 2018; 61(6):355-359 Doi: 10.1111/myc.12757 [OPEN ACCESS]
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Leading authors Med Uni Graz
Hönigl Martin
Prattes Jürgen
Co-authors Med Uni Graz
Eigl Susanne
Heldt Sven
Kessler Harald
Stelzl Evelyn
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Abstract:
The newly developed AspID PCR assay for detection of Aspergillus spp. was evaluated with an interlaboratory quality control programme panel and human bronchoalveolar lavage fluid (BALF) samples. With the quality control programme, 8 out of 9 panel members were correctly identified. With the clinical study, 36 BALF samples that had been obtained from 18 patients with invasive pulmonary aspergillosis (IPA) and 18 without IPA were investigated. Sensitivity, specificity, positive and negative likelihood ratio for the AspID assay were 94.1% (95% CI 73.3-99.9), 76.5% (95% CI 50.1-93.2), 4 (95% CI 1.7-9.5) and 0.1 (95% CI 0.01-0.5) respectively. © 2018 Blackwell Verlag GmbH.

Find related publications in this database (Keywords)
Asp
ID
BALF
galactomannan
invasive aspergillosis
PCR
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