Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Prattes, J; Hoenigl, M; Zinke, SE; Heldt, S; Eigl, S; Johnson, GL; Bustin, S; Stelzl, E; Kessler, HH.
Evaluation of the new AspID polymerase chain reaction assay for detection of Aspergillus species: A pilot study.
Mycoses. 2018; 61(6):355-359
Doi: 10.1111/myc.12757
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- Führende Autor*innen der Med Uni Graz
- Hönigl Martin
- Prattes Jürgen
- Co-Autor*innen der Med Uni Graz
- Eigl Susanne
- Heldt Sven
- Kessler Harald
- Stelzl Evelyn
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- Abstract:
- The newly developed AspID PCR assay for detection of Aspergillus spp. was evaluated with an interlaboratory quality control programme panel and human bronchoalveolar lavage fluid (BALF) samples. With the quality control programme, 8 out of 9 panel members were correctly identified. With the clinical study, 36 BALF samples that had been obtained from 18 patients with invasive pulmonary aspergillosis (IPA) and 18 without IPA were investigated. Sensitivity, specificity, positive and negative likelihood ratio for the AspID assay were 94.1% (95% CI 73.3-99.9), 76.5% (95% CI 50.1-93.2), 4 (95% CI 1.7-9.5) and 0.1 (95% CI 0.01-0.5) respectively. © 2018 Blackwell Verlag GmbH.
- Find related publications in this database (Keywords)
- Asp
- ID
- BALF
- galactomannan
- invasive aspergillosis
- PCR