Medizinische Universität Graz - Research portal
Selected Publication:
Mandak, M; Kerbl, U; Kleinert, R; Höfler, G; Zeichen, R; Denk, H.
Miliary tuberculosis of the liver as a cause of septic shock with multi-organ failure
Wien Klin Wochenschr. 1994; 106(4):111-114
(- Case Report)
Web of Science
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- Co-authors Med Uni Graz
- Denk Helmut
- Höfler Gerald
- Kleinert Reinhold
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- Abstract:
- A woman aged 63 presented with septic fever, followed by hepatocellular jaundice. Viral hepatitis was ruled out by serologic tests, but no definite diagnosis could be made. Due to severe disturbance of the plasmatic coagulatory system and a serum bilirubin level above 4 mg/dl, a liver biopsy was not performed. The patient had a persistent septicemia refractory to Imipenem. In spite of intensive care measures, the patient died of disseminated intravascular coagulation and multiorgan failure caused by septic shock. The correct diagnosis of miliary tuberculosis was made only post mortem by histopathological examination of liver specimens and confirmed by detection of Mycobacterium tuberculosis DNA in the patient's liver by polymerase chain reaction.
- Find related publications in this database (using NLM MeSH Indexing)
- DNA, Bacterial - analysis
- Diagnosis, Differential - analysis
- Female - analysis
- Humans - analysis
- Liver - pathology
- Middle Aged - pathology
- Multiple Organ Failure - etiology
- Mycobacterium tuberculosis - genetics
- Polymerase Chain Reaction - genetics
- Shock, Septic - etiology
- Tuberculosis, Hepatic - complications
- Tuberculosis, Miliary - complications
- Find related publications in this database (Keywords)
- Miliary Tuberculosis
- Septicemia
- Disseminated Intravascular Coagulation
- Liver Biopsy
- Multiorgan Failure
- Polymerase Chain Reaction