Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Plath, J; Siebenhofer, A; Guethlin, C; Blumenstein, I.
Screening interval recommendations following a normal colonoscopy in individuals with a familial risk of colorectal cancer.
Z Gastroenterol. 2018; 56(4):361-364 Doi: 10.1055/s-0043-123882
Web of Science PubMed FullText FullText_MUG

Führende Autor*innen der Med Uni Graz: Siebenhofer-Kroitzsch Andrea
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Abstract:: In view of the increased risk of developing colorectal cancer (CRC) in individuals with affected first-degree relatives (FDRs), the German evidence-based S3 guideline recommends having the first screening colonoscopy early and then, following a normal examination, repeating it at least every 10 years. The aim of this analysis was to explore colonoscopy interval recommendations in clinical practice among individuals aged < 55 years with a familial risk of CRC. We analyzed data from the FRIDA.Frankfurt study. Patients aged 40 - 54 years with at least 1 reported FDR with CRC (excluding suspected/known hereditary cancer syndromes) and a normal colonoscopy result (no findings) were included. Data on colonoscopist recommendations for intervals between subsequent colonoscopies were extracted from colonoscopy reports. Of 63 reports of normal colonoscopies, 20 (32 %) did not include a recommendation on when to undergo a further colonoscopy. Of 43 reports with recommendations, 40 (93 %) suggested an interval that was shorter than the recommended maximum interval in the guideline: 1 (2 %) was for a 3-year interval, 37 (86 %) were for 5-year intervals, and 2 (5 %) were for 8-year intervals. Although the low number of cases limits generalizability, the results indicate that recommended intervals in clinical practice are considerably shorter than the recommended maximum interval in the guideline. © Georg Thieme Verlag KG Stuttgart · New York.
Find related publications in this database (Keywords): colorectal neoplasms; familial risk; colonoscopy; surveillance; screening