Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Sundl, I; Resch, U; Bergmann, AR; Roob, JM; Winklhofer-Roob, BM.
The decrease in gamma-tocopherol in plasma and lipoprotein fractions levels off within two days of vitamin E supplementation.
Ann N Y Acad Sci. 2004; 1031(1):378-380
Doi: 10.1196/annals.1331.049
Web of Science
PubMed
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FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Roob Johannes
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- Abstract:
- The effects of vitamin E supplementation on alpha- and gamma-tocopherol concentrations were studied in plasma and lipoprotein fractions of five healthy volunteers taking 1000 IU/day of RRR alpha-tocopherol for 4 days. Although plasma alpha-tocopherol increased, gamma-tocopherol decreased. Compared with baseline, gamma-/alpha-tocopherol ratios decreased from 48 h onward (P < 0.001). They all leveled off within 48 h. From 12 h onward, gamma-/alpha-tocopherol ratios were higher in VLDL and IDL than in LDL and HDL, indicating that gamma-tocopherol is better maintained in triglyceride-rich lipoprotein fractions. These data suggest that vitamin E supplementation exceeding 2 days does not further decrease gamma-tocopherol concentrations.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Dietary Supplements -
- Female -
- Humans -
- Kinetics -
- Lipoproteins - blood
- Lipoproteins, HDL - blood
- Lipoproteins, IDL - blood
- Lipoproteins, LDL - blood
- Lipoproteins, VLDL - blood
- Male - blood
- Time Factors - blood
- Vitamin E - administration and dosage
- alpha-Tocopherol - blood
- gamma-Tocopherol - blood
- Find related publications in this database (Keywords)
- vitamin E
- supplementation
- alpha-tocopherol
- gamma-tocopherol
- alpha-/gamma-tocopherol ratio
- plasma
- lipoproteins
- VLDL
- IDL
- LDL
- HDL