Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Rief, P; Raggam, RB; Hafner, F; Avian, A; Hackl, G; Cvirn, G; Brodmann, M; Gary, T.
Calculation of HAS-BLED Score Is Useful for Early Identification of Venous Thromboembolism Patients at High Risk for Major Bleeding Events: A Prospective Outpatients Cohort Study.
Semin Thromb Hemost. 2018; 44(4):348-352
Doi: 10.1055/s-0037-1607433
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Rief Peter
- Co-Autor*innen der Med Uni Graz
- Avian Alexander
- Brodmann Marianne
- Cvirn Gerhard
- Gary Thomas
- Hackl Gerald
- Hafner Franz
- Raggam Reinhard Bernd
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- Abstract:
- The aim of this study was prospective evaluation of the performance of the HAS-BLED score in predicting major bleeding complications in a real-world outpatient cohort, during long-term anticoagulation for venous thromboembolism (VTE), treated with a broad spectrum of anticoagulants. We analyzed 111 outpatients objectively diagnosed with VTE and treated long-term with various anticoagulants. Patients were grouped in three cohorts based on the anticoagulant regimen. Calculation of the HAS-BLED score and documentation of bleeding events were performed every 6 months for 1 year. Patients with a HAS-BLED score ≥ 3 had an increased risk for major bleeding events (odds ratio [OR]: 13.05, 95% confidence interval [CI]: 0.96-692.58, p = 0.028) and a trend to higher risk for minor bleeding events as well (OR: 2.25, 95% CI: 0.87-5.85, p = 0.091) when compared with patients with a HAS-BLED score < 3.This indicates that a HAS-BLED score ≥ 3 allows for identification of patients with VTE on long-term anticoagulation at an increased risk for major bleeding events, irrespective of the anticoagulant agent used. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Aged -
- Aged, 80 and over -
- Anticoagulants - administration & dosage
- Anticoagulants - adverse effects
- Female -
- Follow-Up Studies -
- Hemorrhage - chemically induced
- Hemorrhage - epidemiology
- Humans -
- Male -
- Middle Aged -
- Outpatients -
- Prospective Studies -
- Risk Factors -
- Venous Thromboembolism - drug therapy
- Venous Thromboembolism - epidemiology
- Find related publications in this database (Keywords)
- HAS-BLED score
- venous thromboembolism
- bleeding complications
- anticoagulant treatment