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Jajić, I; Benčić, A; Siroglavić, M; Zarfel, G; Ružić, B; Pezelj, I; Bedenić, B.
Klebsiella Pneumoniaeoxa-48 in a Urology Patient: Case Report
Acta Clin Croat. 2017; 56(1):166-171
Doi: 10.20471/acc.2017.56.01.23
(- Case Report)
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- Co-authors Med Uni Graz
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Zarfel Gernot
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- Abstract:
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We present an isolate of Klebsiella pneumoniae OXA-48 isolated in a 68-year-old
man who underwent radical prostatectomy due to prostate cancer. The antibiotic susceptibility testing
to a wide range of antibiotics was performed by disk diffusion method and determination of minimal
inhibitory concentrations. The isolate was classified as multidrug-resistant. It showed intermediate
susceptibility to imipenem and meropenem, resistance to ertapenem, and sensitivity only to colistin,
amikacin, and trimethoprim-sulfamethoxazole. The isolate was positive for ESBLs, negative for
AmpC. Polymerase chain reaction and sequencing revealed bla(OXA-48)', bla(CTX-M-15) and bla(SHV-11). The plasmid
encoding OXA-48 ß-lactamase did not belong to any known PCR-based replicon typing. According
to genotyping, the isolate belonged to ST37.
- Find related publications in this database (using NLM MeSH Indexing)
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Aged -
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Anti-Bacterial Agents - therapeutic use
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Drug Resistance, Multiple, Bacterial - genetics
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Genotype -
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Humans -
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Klebsiella Infections - drug therapy
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Klebsiella Infections - microbiology
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Klebsiella pneumoniae - genetics
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Male -
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Microbial Sensitivity Tests -
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Polymerase Chain Reaction -
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Postoperative Complications - drug therapy
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Postoperative Complications - microbiology
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Prostatectomy -
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Prostatic Neoplasms - surgery
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Trimethoprim, Sulfamethoxazole Drug Combination - therapeutic use
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Urinary Tract Infections - drug therapy
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Urinary Tract Infections - microbiology
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beta-Lactamases - genetics
- Find related publications in this database (Keywords)
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Klebsiella pneumoniae, isolation and purification
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Klebsiella infections
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Prostatectomy, complications
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Case reports