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Andrassy, M; Celik, S; Andrassy, J; Lichtenberg, MK; Brodmann, M.
The role of drug-coated balloons in in-stent restenosis.
J CARDIOVASC SURG. 2017; 58(4): 501-507. Doi: 10.23736/S0021-9509.17.09963-3 [OPEN ACCESS]
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Co-authors Med Uni Graz
Brodmann Marianne
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Abstract:
Despite a constantly expanding spectrum of therapeutic options for lower limb artery disease, there is not yet a well-defined consensus on the specific type of endovascular treatment that is best suited. Clinical data on patients with femoropopliteal disease treated with drug-coated balloons have not been elaborated sufficiently, especially in the case of in-stent restenosis. For this review a systematic research of the medical databases (Pubmed) has been conducted. Keywords such as "drug-coated balloons" (DCB), "drug-eluting balloons," "in-stent restenosis", "de novo stenosis", "angioplasty", "superficial femoral artery," "popliteal artery," "above the knee," "below the knee," "peripheral artery disease" (PAD) have been used. Furthermore, data from reviews, original contributions regarding randomized controlled studies, observational studies, registries and single center experiences have been included. Many trials have shown superiority for DCB- over percutaneous transluminal angioplasty-treatment alone in TASC IIA and TASC IIB femoropopliteal lesions. However, the currently available DCB systems are different in terms of efficacy and long-term outcomes depending on their mechanical and pharmacological features. Moreover, angiographic characteristics of femoropopliteal lesions classified by Tosaka seem to influence subsequent outcomes of DCB treatment. Lastly, there is still lack of reliable prospective long-term data regarding DCB technology.
Find related publications in this database (using NLM MeSH Indexing)
Angioplasty, Balloon - adverse effects
Angioplasty, Balloon - instrumentation
Cardiovascular Agents - administration & dosage
Coated Materials, Biocompatible -
Humans -
Lower Extremity - blood supply
Peripheral Arterial Disease - diagnostic imaging
Peripheral Arterial Disease - physiopathology
Peripheral Arterial Disease - therapy
Prosthesis Design -
Recurrence -
Retreatment -
Stents -
Treatment Outcome -
Vascular Access Devices -
Vascular Patency -

Find related publications in this database (Keywords)
Angioplasty, balloon
Coronary restenosis
Stents
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