Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Reinisch, A; Majeti, R.
Sticking It to the Niche: CD98 Mediates Critical Adhesive Signals in AML.
Cancer Cell. 2016; 30(5): 662-664.
Doi: 10.1016/j.ccell.2016.10.014
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- Führende Autor*innen der Med Uni Graz
- Reinisch Andreas
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- Abstract:
- In this issue of Cancer Cell, Bajaj and colleagues report that CD98, a heterodimeric protein highly expressed in acute myeloid leukemia (AML) and largely dispensable for basal hematopoiesis, plays an important role in facilitating leukemia stem cell adhesion to bone marrow vasculature and is a potential therapeutic target in AML. Copyright © 2016 Elsevier Inc. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Adhesives - metabolism
- Bone Marrow - metabolism
- Bone Marrow Cells - metabolism
- Hematopoiesis -
- Humans -
- Leukemia, Myeloid, Acute - drug therapy