Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Högenauer, C; Hammer, HF; Krejs, GJ; Reisinger, EC.
Mechanisms and management of antibiotic-associated diarrhea.
Clin Infect Dis. 1998; 27(4):702-710
Doi: 10.1086/514958
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- Führende Autor*innen der Med Uni Graz
- Hoegenauer Christoph
- Co-Autor*innen der Med Uni Graz
- Hammer Heinz
- Krejs Günter Josef
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- Abstract:
- Only 10%-20% of all cases of antibiotic-associated diarrhea (AAD) are caused by infection with Clostridium difficile. Other infectious organisms causing AAD include Clostridium perfringens, Staphylococcus aureus, Klebsiella oxytoca, Candida species, and Salmonella species. Most of the clinically mild AAD cases are due to functional disturbances of intestinal carbohydrate or bile acid metabolism, to allergic and toxic effects of antibiotics on intestinal mucosa, or to pharmacological effects on motility. Saccharomyces boulardii and Enterococcus SF68 can reduce the risk of developing AAD. Patients receiving antibiotic treatment should avoid food containing high amounts of poorly absorbable carbohydrates. Mild cases of AAD that may or may not be caused by C. difficile can be resolved by discontinuation of antibiotic therapy and by dietary carbohydrate reduction. Only severe AAD caused by C. difficile requires specific antibiotic treatment.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Anti-Bacterial Agents - adverse effects
- Diarrhea - chemically induced Diarrhea - microbiology Diarrhea - prevention and control Diarrhea - therapy
- Disease Management -
- Humans -