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Mörkl, S; Tmava, A; Blesl, C; Schmiedhofer, F; Wurm, WE; Holl, A; Painold, A.
[The power plants of the cell: Treatment of psychiatric symptoms in patients with mitochondriopathy].
Fortschr Neurol Psychiatr. 2017; 85(8):474-478 Doi: 10.1055/s-0043-113824 (- Case Report)
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Führende Autor*innen der Med Uni Graz
Leal Garcia Sabrina
Co-Autor*innen der Med Uni Graz
Holl Anna
Mittmannsgruber Claudia
Painold Annamaria
Schmiedhofer Franziska
Tmava-Berisha Adelina
Wurm Walter Ernst
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Abstract:
Introduction Mitochondriopathies are pathologies of cell organelles, which are essential for the formation of adenosine triphosphate (ATP), which is responsible for cellular energy stock. When mitochondrial mutations occur, symptoms arise frequently in those organs that rely on a continuous energy supply, such as the nervous system. Although psychiatric illness is increasingly prevalent in patients with mitochondrial disease, less attention has been paid to its psychiatric presentations. Case Report We describe a case of a 21-year-old woman who presented in our outpatient department with panic attacks and depression. The patient experienced major side effects after low-dose sertraline therapy. Conclusion Mitochondriopathies belong to the class of rare illnesses in psychiatry; nevertheless, they require adaptations of psychopharmacological therapy. Psychotropic drugs are potential respiratory chain inhibitors and could lead to distinct side effects. Georg Thieme Verlag KG Stuttgart · New York.
Find related publications in this database (using NLM MeSH Indexing)
Depressive Disorder - drug therapy
Depressive Disorder - etiology
Female -
Humans -
Mitochondrial Diseases - complications
Mitochondrial Diseases - drug therapy
Mitochondrial Diseases - psychology
Neuropsychological Tests -
Panic Disorder - drug therapy
Panic Disorder - etiology
Personality -
Serotonin Uptake Inhibitors - adverse effects
Serotonin Uptake Inhibitors - therapeutic use
Sertraline - adverse effects
Sertraline - therapeutic use
Treatment Outcome -
Young Adult -

Find related publications in this database (Keywords)
Mitochondriopathie
Panikstorung
Depression
Psychiatrie
Psychopharmakologie
mitochondriopathy
panic disorder
depression
psychiatry
psychopharmacology
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