Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Herrmann, M; Scholmerich, J; Straub, RH.
Influence of cytokines and growth factors on distinct steroidogenic enzymes in vitro: a short tabular data collection.
Ann N Y Acad Sci. 2002; 966(8):166-186
Doi: 10.1111/j.1749-6632.2002.tb04213.x
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Herrmann Markus
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- Abstract:
- Cytokines (IL-1, IL-6, IL-8, IL-11, TNF, IFN-gamma, and TGF-beta) and growth factors (EGF, bFGF, aFGF, and KGF) play an important role in modulation of hormone secretion by directly influencing specific enzyme steps of steroidogenesis in various endocrine cell types. For this tabular data collection, the following enzyme steps were considered: steroidogenic acute regulatory protein (StAR), side chain cleavage enzyme (P450scc), 3 beta-hydroxysteroid dehydrogenase, 17-alpha-hydroxylase/17,20-lyase (P450c17), 17-beta-hydroxysteroid-dehydrogenase, aromatase complex, 5-alpha-reductase, P450c21, DHEAS sulfatase, and DHEA sulfotransferase. This collection summarizes the current information on how the mentioned cytokines and growth factors influence particular enzyme steps.
- Find related publications in this database (using NLM MeSH Indexing)
- 17-Hydroxysteroid Dehydrogenases - biosynthesis
- 17-Hydroxysteroid Dehydrogenases - genetics
- 3-Hydroxysteroid Dehydrogenases - biosynthesis
- 3-Hydroxysteroid Dehydrogenases - genetics
- 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - biosynthesis
- 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - genetics
- Animals -
- Aromatase - biosynthesis
- Aromatase - genetics
- Cattle -
- Cells, Cultured - drug effects
- Cells, Cultured - enzymology
- Cholesterol Side-Chain Cleavage Enzyme - biosynthesis
- Cholesterol Side-Chain Cleavage Enzyme - genetics
- Chronic Disease -
- Cytokines - pharmacology
- Enzyme Induction - drug effects
- Female -
- Growth Substances - pharmacology
- Humans -
- Inflammation - enzymology
- Male -
- Mice -
- Phosphoproteins - biosynthesis
- Phosphoproteins - genetics
- Rats -
- Steroid 17-alpha-Hydroxylase - biosynthesis
- Steroid 17-alpha-Hydroxylase - genetics
- Steroids - biosynthesis
- Find related publications in this database (Keywords)
- cytokines
- growth factors
- steroidogenic enzymes
- data collection