Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Sambrook, PN; Cameron, ID; Chen, JS; Cumming, RG; Durvasula, S; Herrmann, M; Kok, C; Lord, SR; Macara, M; March, LM; Mason, RS; Seibel, MJ; Wilson, N; Simpson, JM.
Does increased sunlight exposure work as a strategy to improve vitamin D status in the elderly: a cluster randomised controlled trial.
Osteoporos Int. 2012; 23(2):615-624
Doi: 10.1007/s00198-011-1590-5
Web of Science
PubMed
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- Herrmann Markus
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- Abstract:
- Sunlight exposure by improving vitamin D status could be a simple public health strategy in reducing falls among frail elder people. In a randomised controlled trial, adherence to sunlight exposure was low (median adherence, 26%) and no effect of increased UV exposure on falls risk was observed (incidence rate ratio (IRR) 1.06, P = 0.73). This study aimed to determine whether increased sunlight exposure was effective to improve vitamin D status and reduce falls in the elderly. In a cluster randomised controlled trial (NCT00322166 at ClinicalTrials.gov), 602 residents aged 70 or more (mean age, 86.4 years; 71% female) were recruited from 51 aged care facilities in Northern Sydney, Australia. Participants were randomised by facility to receive either increased sunlight exposure (additional 30-40 min/day in the early morning) with (UV+) or without (UV) calcium supplementation (600 mg/day) or neither (control) for a year. The co-primary endpoints were change in serum 25 hydroxy vitamin D (25OHD) and falls incidence after 12 months. Adherence to sunlight exposure was low (median adherence, 26%; IQR, 7%-45%). Serum 25OHD levels were low at baseline (median, 32.9 nmol/L) and increased only slightly depending on the number of sunlight sessions attended over 12 months (P = 0.04). During the study, 327 falls occurred in 111 (54%) subjects in the control group, 326 falls in 111 (58%) subjects in the UV only group and 335 falls in 108 (52%) subjects in the UV+ group. By intention-to-treat analysis, there was no significant effect of increased UV exposure on falls risk (IRR, 1.06; 95% CI, 0.76-1.48; P = 0.73). However, in 66 participants who attended ≥130 sessions per year (adherence, ≥50% of 260 sessions-five per week), falls were significantly reduced (IRR, 0.52; 95% CI, 0.31-0.88; P = 0.01) compared with the control group. Increased sunlight exposure did not reduce vitamin D deficiency or falls risk in frail older people. This public health strategy was not effective most likely due to poor adherence to the intervention.
- Find related publications in this database (using NLM MeSH Indexing)
- Accidental Falls - prevention & control
- Aged -
- Aged, 80 and over -
- Calcium Carbonate - therapeutic use
- Dietary Supplements -
- Female -
- Fractures, Bone - prevention & control
- Heliotherapy - adverse effects
- Heliotherapy - methods
- Heliotherapy - psychology
- Homes for the Aged -
- Humans -
- Male -
- Patient Compliance - statistics & numerical data
- Treatment Outcome -
- Vitamin D - analogs & derivatives
- Vitamin D - blood
- Vitamin D Deficiency - blood
- Vitamin D Deficiency - therapy
- Find related publications in this database (Keywords)
- Aged care facility
- Elderly
- Falls
- Sunlight exposure
- Vitamin D deficiency