Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Farrell, CJ; Herrmann, M.
Determination of vitamin D and its metabolites.
Best Pract Res Clin Endocrinol Metab. 2013; 27(5):675-688
Doi: 10.1016/j.beem.2013.06.001
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Herrmann Markus
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- The demand for analysis of 25-hydroxyvitamin D has increased dramatically throughout the world over the past decade. As a consequence, a number of new automated assays have been introduced for 25-hydroxyvitamin D measurement. Automated assays have shown variable ability to meet the technical challenges associated with 25-hydroxyvitamin D measurement. Assays are able to meet performance goals for precision at high concentrations but fail to do so at low concentrations of 25-hydroxyvitamin D. The overall accuracy of automated methods has improved over recent years and generally shows good overall agreement with reference methods; however, discrepancies persist for individual samples. Liquid chromatography-tandem mass spectrometry is used by some routine laboratories for 25-hydroxyvitamin D analysis but its widespread use is hampered by limited sample throughput. 1,25-Dihydroxyvitamin D is an important analyte in specific clinical situations, which remains in the hands of specialised laboratories using manual analytical methods. Copyright © 2013 Elsevier Ltd. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Autoanalysis -
- Cholecalciferol - biosynthesis
- Cholecalciferol - metabolism
- Chromatography, High Pressure Liquid -
- Chromatography, Liquid -
- Humans -
- Hydroxylation -
- Infant -
- Protein Binding -
- Radioimmunoassay -
- Reproducibility of Results -
- Tandem Mass Spectrometry -
- Vitamin D - analogs & derivatives
- Vitamin D - blood
- Vitamin D - metabolism
- Find related publications in this database (Keywords)
- 25-hydroxyvitamin D
- immunoassays
- high-performance liquid chromatography
- liquid chromatography-tandem
- mass spectrometry