Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Husic, R; Lackner, A; Stradner, MH; Hermann, J; Dejaco, C.
Joint positions matter for ultrasound examination of RA patients-increased power Doppler signal in neutral versus flat position of hands.
Rheumatology (Oxford). 2017; 56(8):1312-1319
Doi: 10.1093/rheumatology/kex153
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- Führende Autor*innen der Med Uni Graz
- Dejaco Christian
- Husic Rusmir
- Co-Autor*innen der Med Uni Graz
- Hermann Josef
- Lackner Angelika
- Stradner Martin Helmut
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- Abstract:
- OBJECTIVE: Position of joints might influence the result of US examination in patients with RA. The purpose of this work was to compare grey-scale (GS) and power Doppler (PWD) findings obtained in neutral vs flat position of hands. METHODS: A cross-sectional study of 42 RA patients with active disease. Two dimensional and 3D sonography of wrists and MCP joints were conducted in two different joint positions: neutral position, which is a slight flexion of the fingers with relaxed extensor muscles; and flat position, where all palm and volar sides of fingers touch the Table. Two dimensional GS synovitis (GSS) and PWD signals were scored semi-quantitatively (0-3). For 3D sonography, the percentage of PWD voxels within a region of interest was calculated. GSS was not quantified using 3D sonography. RESULTS: Compared with neutral position, 2D PWD signals disappeared in 28.3% of joints upon flattening. The median global 2D PWD score (sum of all PWD scores of an individual patient) decreased from 8 to 3 ( P < 0.001), and the global 3D PWD voxel score from 3.8 to 0.9 ( P < 0.001). The reduction of PWD scores was similar in all joints (2D: minus 50%, 3D: minus 66.4-80.1%). Inter- and intrareader agreement of PWD results was good (intraclass correlation coefficient: 0.75-0.82). CONCLUSION: In RA, a neutral position of the hands is linked to a higher sensitivity of 2D and 3D sonography in detecting PWD signals at wrists and MCP joints, compared with a flat position. Standardization of the scanning procedure is essential for obtaining comparable US results in RA patients in trials and clinical routines.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult - administration & dosage
- Aged - administration & dosage
- Arthritis, Rheumatoid - diagnostic imaging
- Cross-Sectional Studies - administration & dosage
- Female - administration & dosage
- Hand Joints - diagnostic imaging
- Humans - administration & dosage
- Imaging, Three-Dimensional - methods
- Male - administration & dosage
- Middle Aged - administration & dosage
- Patient Positioning - methods
- Sensitivity and Specificity - administration & dosage
- Synovitis - diagnostic imaging
- Ultrasonography, Doppler - methods
- Wrist Joint - diagnostic imaging
- Find related publications in this database (Keywords)
- rheumatoid arthritis
- hand
- diagnostic imaging
- ultrasonography
- wrist