Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Hoeller, A; Ehrlich, L; Golic, M; Herse, F; Perschel, FH; Siwetz, M; Henrich, W; Dechend, R; Huppertz, B; Verlohren, S.
Placental expression of sFlt-1 and PlGF in early preeclampsia vs. early IUGR vs. age-matched healthy pregnancies.
Hypertens Pregnancy. 2017; 36(2):151-160
Doi: 10.1080/10641955.2016.1273363
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Huppertz Berthold
- Siwetz Monika
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- Abstract:
- To investigate whether differences between early preeclampsia and early fetal growth restriction can be explained by differential placental expression patterns of sFlt-1, Flt-1, and PlGF. Placental tissues and maternal blood samples from six cases of preeclampsia, seven IUGR, and six age-matched controls were studied for mRNA and protein levels as well as protein localization and expression intensity. Neither placental PlGF mRNA and protein expression nor placental villous trophoblast expression intensity of PlGF was altered by placental dysfunction. High sFlt-1 concentrations may account for diminished maternal serum PlGF levels.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Case-Control Studies -
- Female -
- Fetal Growth Retardation - metabolism
- Humans -
- Placenta - metabolism
- Placenta Growth Factor - metabolism
- Pre-Eclampsia - metabolism
- Pregnancy -
- Vascular Endothelial Growth Factor Receptor-1 - metabolism
- Find related publications in this database (Keywords)
- sFlt-1
- PlGF
- sFlt-1
- PlGF
- preeclampsia
- intrauterine growth restriction