Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Friesenbichler, J; Maurer-Ertl, W; Bergovec, M; Holzer, LA; Ogris, K; Leitner, L; Leithner, A.
Clinical experience with the artificial bone graft substitute Calcibon used following curettage of benign and low-grade malignant bone tumors.
Sci Rep. 2017; 7(1):1736-1736
Doi: 10.1038/s41598-017-02048-w
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- Führende Autor*innen der Med Uni Graz
- Friesenbichler Jörg
- Co-Autor*innen der Med Uni Graz
- Bergovec Marko
- Holzer Lukas
- Leithner Andreas
- Leitner Lukas
- Maurer-Ertl Werner
- Ogris Kathrin
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- Abstract:
- Artificial bone graft substitutes, such as Calcibon, are becoming increasingly interesting as they do not cause donor site morbidity which is an advantage compared to autologous bone grafts. The aim of this study was to evaluate the efficacy and potential complications associated with the use of Calcibon. Twenty-seven patients with benign and low-grade malignant bone tumors were treated with curettage and refilling of the bony cavity. Based on the radiological classification system of Neer, these lesions only comprised Grade I lesions, describing cysts that only require curettage and filling, but no additional treatment. At a mean follow up of six months we observed radiological consolidation without resorption of the bone graft substitute. These observations were also made at a mean follow-up of 13 and 32 months, respectively. According to the classification system of Goslings and Gouma we observed six surgical complications. Summing up, Calcibon seems to be a reliable bone graft substitute with low complication rates. However, delayed resorption should be expected. Calcibon seems to be an alternative to autologous bone grafts or allografts in adequate indications.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Aged -
- Bone Neoplasms - complications
- Bone Neoplasms - diagnostic imaging
- Bone Neoplasms - pathology
- Bone Neoplasms - therapy
- Bone Substitutes - pharmacology
- Bone Transplantation -
- Curettage - adverse effects
- Female -
- Humans -
- Male -
- Middle Aged -
- Young Adult -