Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Woltsche, N; Schmid-Zalaudek, K; Deinlein, T; Rammel, K; Hofmann-Wellenhof, R; Zalaudek, I.
Abundance of the benign melanocytic universe: Dermoscopic-histopathological correlation in nevi.
J Dermatol. 2017; 44(5):499-506
Doi: 10.1111/1346-8138.13808
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- Führende Autor*innen der Med Uni Graz
- Woltsche Nora
- Zalaudek Iris
- Co-Autor*innen der Med Uni Graz
- Hofmann-Wellenhof Rainer
- Kränke Teresa Maria
- Schmid-Zalaudek Karin
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- Abstract:
- The broad universe of "melanocytic nevi" includes a variety of different subtypes, which can be classified either due to their morphology, epidemiology, genetic alterations or risk for developing melanoma. Regarding morphology, on the one hand macroscopic/clinical and on the other hand histopathological appearance were used to subdivide in the past, often resulting in confusion and poor interobserver agreement, while nowadays dermoscopy presents the clinician's precious bridge between naked-eye examination and histopathological diagnostics, allowing prediction of the lesions' histopathology, follow up and monitoring over time without need of excision. The non-invasive dermoscopic examination relies on the assessment of colors, patterns and the distribution of both within a cutaneous lesion. Until today, the correspondence of certain dermoscopic colors and patterns to certain histopathological correlates has been reported for a huge amount of different cutaneous lesions. Moreover, the correspondence of certain dermoscopic features to certain body sites, age groups and pigmentary traits, but also to specific genetic alterations in lesions, has been broadly investigated. Dermoscopy has led us to a new understanding of melanocytic nevi's biology and evolution and, last but not least, to a new classification system, which we want to present herein. © 2017 Japanese Dermatological Association.
- Find related publications in this database (using NLM MeSH Indexing)
- Dermoscopy -
- Humans -
- Nevus, Pigmented - classification
- Nevus, Pigmented - pathology
- Skin - pathology
- Find related publications in this database (Keywords)
- dermoscopy
- histopathology
- melanoma
- nevi
- nevogenesis