Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Ropele, S; Enzinger, C; Fazekas, F.
Iron Mapping in Multiple Sclerosis.
Neuroimaging Clin N Am. 2017; 27(2):335-342
Doi: 10.1016/j.nic.2016.12.003
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Ropele Stefan
- Co-authors Med Uni Graz
- Enzinger Christian
- Fazekas Franz
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- Abstract:
- Increased iron deposition in cerebral deep gray matter has been considered a global marker for neurodegeneration in multiple sclerosis (MS); it scales with disease duration and severity. Iron accumulation in white matter and MS lesions might be more directly related to disease activity and has been discussed as a contributor to the inflammatory and neurodegenerative cascade. New insights into iron and MS are expected from MR imaging. We discuss findings from MR iron mapping proposed. Because of the confounding magnetic properties of myelin, iron mapping in white matter remains an unresolved issue. Copyright © 2016 Elsevier Inc. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Brain - metabolism
- Brain - pathology
- Humans -
- Image Interpretation, Computer-Assisted -
- Iron - metabolism
- Magnetic Resonance Imaging - methods
- Multiple Sclerosis - diagnosis
- Multiple Sclerosis - metabolism
- White Matter -
- Find related publications in this database (Keywords)
- Iron
- Ferritin
- Multiple sclerosis
- MR imaging
- Magnetic susceptibility
- Neurodegeneration
- Biomarker