Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Jasser-Nitsche, H; Varga, EM; Borkenstein, HM; Höntzsch, J; Suppan, E; Weinhandl, G; Pieringer, L; Avian, A; Fröhlich-Reiterer, E.
Type 1 diabetes in children and adolescents is not associated with a reduced prevalence of atopy and allergic diseases.
Pediatr Diabetes. 2017; 18(8):890-894
Doi: 10.1111/pedi.12504
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Jasser-Nitsche Hildegard
- Co-Autor*innen der Med Uni Graz
- Avian Alexander
- Borkenstein Helmuth Martin
- Fröhlich-Reiterer Elke
- Varga Eva-Maria
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- Abstract:
- Type 1 diabetes mellitus (T1D) as well as allergies in childhood have increased worldwide during the last 2 decades. The reasons for this increase are still unknown but early life origins are being discussed, such as dietary and hygiene factors that may play a role in the development of both diseases. The aim of this study was to compare the prevalence of allergies in children with and without T1D and to define potential influencing factors. Data were collected from 104 patients with T1D (n = 104; mean age 11.4 ± 4.4 years; m/f: 77/27) and 104 healthy controls (CG) (n = 104; mean age 11.4 ± 4.3 years; m/f: 77/27). A questionnaire on allergic symptoms was obtained from each individual. In parallel, ImmunoCAP tests to detect specific allergen sensitization were performed. Allergen sensitization rates were not significantly different between both groups (T1D: 42% vs CG 38%; P = 0.625). In both groups, a comparable number of patients reported allergic symptoms in the questionnaire (T1D: 20% vs CG 26%; P = 0.43). Allergen sensitization and allergic symptoms were independent of breastfeeding, pets at home or diabetes duration. However, in T1D, fewer family members smoked (T1D: 10% vs CG 56%; P < 0.001). The present cohort study shows the same prevalence of allergy and atopy in a pediatric diabetes population compared to healthy controls. Diabetes per se does not seem to influence the development of allergies. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Animals -
- Austria - epidemiology
- Breast Feeding -
- Case-Control Studies -
- Child -
- Cohort Studies -
- Diabetes Mellitus, Type 1 - complications
- Diabetes Mellitus, Type 1 - epidemiology
- Diabetes Mellitus, Type 1 - immunology
- Female -
- Humans -
- Hypersensitivity - complications
- Hypersensitivity - epidemiology
- Immunoglobulin E -
- Male -
- Pets -
- Prevalence -
- Find related publications in this database (Keywords)
- allergy
- atopy
- children
- prevalence
- T1D