Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Roudenok, V; Gutjar, L; Antipova, V; Rogov, Y.
Expression of vasoactive intestinal polypeptide and calcitonin gene-related peptide in human stellate ganglia after acute myocardial infarction.
Ann Anat. 2001; 183(4):341-344
Doi: 10.1016/S0940-9602(01)80176-X
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- Co-Autor*innen der Med Uni Graz
- Antipova Veronica Alexandra
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- Abstract:
- Using the method of indirect immunofluorescence the distribution of vasoactive intestinal polypeptide (VIP) and calcitonin gene-related peptide (CGRP) was investigated in autopsy specimens of human stellate ganglia following acute myocardial infarction (AMI). The dramatic increase of both VIP- and CGRP-immunoreactivities in principal ganglionic neurons as well as of calcitonin gene-related peptide in perineuronal nets was revealed. It was concluded that hypoxia and myocardial ischaemia following AMI are the main inducing factors for activation of both vasoactive regulatory neuropeptide synthesis. The upregulation of VIP and CGRP expression in sympathetic ganglionic neurons may provide regulatory and trophic support to the ischaemic heart.
- Find related publications in this database (using NLM MeSH Indexing)
- Autopsy -
- Calcitonin Gene-Related Peptide - analysis
- Humans -
- Middle Aged -
- Myocardial Infarction - pathology
- Nerve Fibers - pathology
- Nerve Fibers - ultrastructure
- Neurons - cytology
- Neurons - pathology
- Reference Values -
- Stellate Ganglion - cytology
- Stellate Ganglion - pathology
- Vasoactive Intestinal Peptide - analysis
- Find related publications in this database (Keywords)
- stellate ganglia
- CGRP
- VIP
- acute myocardial infarction