Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Lovrenski, J; Sorantin, E; Stojanović, S; Doronjski, A; Lovrenski, A.
Evaluation of Surfactant Replacement Therapy Effects--A New Potential Role of Lung Ultrasound.
Srp Arh Celok Lek. 2016; 143(11-12): 669-675.
Doi: 10.2298/SARH1512669L
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- Co-Autor*innen der Med Uni Graz
- Sorantin Erich
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- Abstract:
- Previous studies suggested that effects of the surfactant administration in preterm intants with respiratory distress syndrome cannot be followed by lung ultrasound (L-US). The aim of the paper is to evaluate the surfactant replacement therapy effects using a new, proposed grading system for L-US findings. We report the series of 12 preterm infants with clinical and radiographic signs of respiratory distress syndrome, in whom L-US examinations were performed prior to, and within the first 24 hours after surfactant administration. To evaluate the surfactant replacement therapy effects, we proposed a new grading system (1 to 6) for L-US findings at each examined lung area, based on the presence of normal finding, the amount of B-lines and subpleural consolidations. All preterm infants had an improvement of L-US findings from one to four grades observed within the first 24 hours after surfactant administration, which has not been previously reported. The improvement of L-US findings was most commonly observed in anterior lung areas. L-US might enable an early detection of the surfactant replacement therapy effects. Further prospective studies are necessary to define the role of L-US in this field.
- Find related publications in this database (using NLM MeSH Indexing)
- Female -
- Humans -
- Infant, Newborn -
- Infant, Premature -
- Male -
- Prospective Studies -
- Pulmonary Surfactants - therapeutic use
- Respiratory Distress Syndrome, Newborn - diagnostic imaging
- Respiratory Distress Syndrome, Newborn - therapy
- Treatment Outcome -
- Ultrasonography -
- Find related publications in this database (Keywords)
- respiratory distress syndrome
- premature
- ultrasound
- lung
- surfactant