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Selected Publication:
Petru, E; Lahousen, M; Tamussino, K; Pickel, H; Stranzl, H; Stettner, H; Winter, R.
Lymphadenectomy in stage I ovarian cancer.
Am J Obstet Gynecol. 1994; 170(2):656-662
Doi: 10.1016/S0002-9378(94)70244-6
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- Leading authors Med Uni Graz
- Petru Edgar
- Co-authors Med Uni Graz
- Lahousen Manfred
- Stranzl-Lawatsch Heidi
- Tamussino Karl
- Winter Raimund
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- Abstract:
- OBJECTIVE: Our experience with systematic lymphadenectomy in stage I ovarian cancer (defined as intraabdominal disease confined to the ovaries) was reviewed. We analyzed whether it would be possible to predict lymph node metastases on the basis of clinical-morphologic factors at the time of surgery. STUDY DESIGN: Forty of 100 evaluable patients operated on between 1980 and 1990 underwent comprehensive surgical staging, including total abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy, and systemic pelvic +/- paraaortic lymphadenectomy. RESULTS: Nine of the 40 (23%) patients who underwent lymphadenectomy were found to have lymph node metastases; five of these were less than or equal to 2 mm in maximum diameter. Four of the nine patients with positive nodes had ovarian tumors with a maximum diameter of only 5 cm, eight had grade 2 or 3 tumors, and eight tumors were classified as serous cystadenocarcinomas. Other clinical-morphologic factors such as ascites, adherence, or extracystic excrescences did not predict lymph node metastasis. Four of the nine patients with positive nodes survived greater than or equal to 5 years with no evidence of disease. CONCLUSIONS: Lymph node metastases, some less than or equal to 2 mm in diameter, occur in an appreciable percentage of patients with intraabdominal disease confined to the ovaries. Clinical-morphologic factors at surgery cannot be relied on to predict the status of the lymph nodes. Thus we cannot recommend limiting lymphadenectomy to any specific subgroup of patients with intraabdominal disease confined to the ovaries.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Carcinoma - drug therapy Carcinoma - pathology Carcinoma - radiotherapy Carcinoma - surgery
- Combined Modality Therapy -
- Female -
- Humans -
- Lymph Node Excision -
- Lymphatic Metastasis -
- Middle Aged -
- Neoplasm Recurrence, Local -
- Neoplasm Staging -
- Ovarian Neoplasms - drug therapy Ovarian Neoplasms - pathology Ovarian Neoplasms - radiotherapy Ovarian Neoplasms - surgery
- Prognosis -
- Find related publications in this database (Keywords)
- Ovarian Cancer
- Stage I Disease
- Lymphadenectomy
- Lymph Node Metastases