Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Tuca, AC; Ertl, J; Hingerl, K; Pichlsberger, M; Fuchs, J; Wurzer, P; Pfeiffer, D; Bubalo, V; Parvizi, D; Kamolz, LP; Lang, I.
Comparison of Matrigel and Matriderm as a carrier for human amnion-derived mesenchymal stem cells in wound healing.
Placenta. 2016; 48:99-103
Doi: 10.1016/j.placenta.2016.10.015
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Lang-Olip Ingrid
- Tuca Alexandru
- Co-authors Med Uni Graz
- Brislinger Dagmar
- Bubalo Vladimir
- Hingerl Kerstin
- Kamolz Lars-Peter
- Parvizi Daryousch
- Pichlsberger Melanie
- Wurzer Paul
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Amnion-derived mesenchymal stem cells (AMSC) are a promising tool in regenerative medicine. Here we evaluated the utility of Matrigel and Matriderm as carrier for the topical application of AMSC to mice skin wounds. In both application forms, AMSC promoted neovascularization of the wound area. Matrigel proved as excellent matrix for AMSC and immigrating mouse cells, but the solid Matriderm enabled a more adequate positioning of AMSC into the wound. Although AMSC did not attach to Matriderm, they reliably induced wound reduction. Thus, a combined administration of AMSC/Matriderm could be beneficial to potentiate the encouraging effects on wound healing. Copyright © 2016 Elsevier Ltd. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Collagen - therapeutic use
- Drug Combinations -
- Elastin - therapeutic use
- Humans -
- Laminin - therapeutic use
- Mesenchymal Stromal Cells - cytology
- Mice -
- Neovascularization, Physiologic - physiology
- Proteoglycans - therapeutic use
- Wound Healing - physiology
- Find related publications in this database (Keywords)
- Human placenta
- Amnion
- Mesenchymal stem cells
- Wound healing
- Angiogenesis
- Mouse model