Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Geltner, C; Errhalt, P; Baumgartner, B; Ambrosch, G; Machan, B; Eckmayr, J; Klikovits, T; Hoda, MA; Popper, H; Klepetko, W; Austrian Mesothelioma Interest Group (AMIG).
Management of malignant pleural mesothelioma - part 1: epidemiology, diagnosis, and staging : Consensus of the Austrian Mesothelioma Interest Group (AMIG).
Wien Klin Wochenschr. 2016; 128(17-18):611-617
Doi: 10.1007/s00508-016-1080-z
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- Co-Autor*innen der Med Uni Graz
- Popper Helmuth
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- Abstract:
- Malignant pleural mesothelioma is a rare malignant disease that in the majority of cases is associated with asbestos exposure. The incidence in Europe is about 20 per million inhabitants and it is increasing worldwide. Initial symptoms are shortness of breath, pleural effusion, cough, and chest pain. The typical growth pattern is along the pleural surface; however, infiltration of the lung and/or mediastinal and chest wall structures can occur in a more advanced stage. Ultimately, distant metastases outside the chest can result. Several histological subtypes of pleural mesothelioma exist, which must be differentiated from either benign diseases or metastases in the pleural space by other tumor entities. This differential diagnosis can be very difficult and a large panel of immunohistochemical markers is required to establish the exact diagnosis. The standard procedure for confirming the disease and obtaining sufficient tissue for the diagnosis is videothoracoscopy. Full thickness biopsies are required, while transthoracic needle puncture of pleural fluid or tissue is considered to be insufficient for a cytological diagnosis. Complete and detailed staging is mandatory for categorization of the disease as well as for therapeutic decision making.
- Find related publications in this database (using NLM MeSH Indexing)
- Diagnosis, Differential -
- Diagnostic Imaging - standards
- Evidence-Based Medicine - standards
- Humans -
- Medical Oncology - standards
- Mesothelioma - diagnosis
- Mesothelioma - epidemiology
- Mesothelioma - pathology
- Neoplasm Staging -
- Pleural Effusion, Malignant - diagnosis
- Pleural Effusion, Malignant - epidemiology
- Pleural Effusion, Malignant - pathology
- Pleural Neoplasms - diagnosis
- Pleural Neoplasms - epidemiology
- Pleural Neoplasms - pathology
- Practice Guidelines as Topic -
- Prevalence -
- Risk Factors -
- Find related publications in this database (Keywords)
- Malignant pleural mesothelioma
- Epidemiology
- Staging
- Pathology
- Diagnosis