Medizinische Universität Graz - Research portal
Selected Publication:
Eber, E; Steinbrugger, B; Modl, M; Weinhandl, E; Zach, MS.
Lung volume measurements in wheezy infants: comparison of plethysmography and gas dilution.
EUR RESP J 1994 7: 1988-1994.
[OPEN ACCESS]
Web of Science
PubMed
- Leading authors Med Uni Graz
- Eber Ernst
- Co-authors Med Uni Graz
- Modl Manfred
- Weinhandl Elisabeth
- Zach Maximilian
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- Abstract:
- The accuracy both of plethysmographic measurements of thoracic gas volume (TGV) and determinations of functional residual capacity (FRC) by gas dilution techniques in infants with obstructive lung disease is subject to continued dispute. We studied 25 wheezy infants and compared TGV derived from end-expiratory airway occlusions (TGVEE), corrected TGV after end-inspiratory airway occlusions (TGVEI), and FRC determined by nitrogen wash-out (FRCN2). Group mean TGVEE and TGVEI differed significantly (25.8 +/- 8.4 versus 24.6 +/- 7.1 ml.kg-1). TGVEE and FRCN2 did not differ significantly. TGVEE and TGVEI, as well as TGVEE and FRCN2, and TGVEI and FRCN2 data, respectively, showed lack of agreement. Based on 95% confidence intervals, calculated from TGVEE data, 14 of the 25 infants showed a significantly higher TGVEI than TGVEE; only one patient had a significantly lower TGVEI. Compared to FRCN1 data, TGVEE and TGVEI measurements yielded lower values in at least one third of our patients. The present study illustrates, that there is no gold standard for the measurement of lung volume in infants with airway obstruction.
- Find related publications in this database (using NLM MeSH Indexing)
- Bronchiolitis, Viral - diagnosis
- Female - diagnosis
- Functional Residual Capacity - diagnosis
- Humans - diagnosis
- Indicator Dilution Techniques - diagnosis
- Infant - diagnosis
- Lung Volume Measurements - methods
- Male - methods
- Nitrogen - diagnostic use
- Plethysmography, Whole Body - diagnostic use
- Reproducibility of Results - diagnostic use
- Respiratory Sounds - diagnosis
- Find related publications in this database (Keywords)
- Lung Volume
- Nitrogen Wash-Out
- Plethysmography
- Wheezy Infants