Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Liu, DT; Friesenbichler, J; Holzer, LA; Liegl-Atzwanger, B; Beham-Schmid, C; Leithner, A.
Langerhans cell sarcoma: a case report and review of the literature.
Pol J Pathol. 2016; 67(2):172-178
Doi: 10.5114/PJP.2016.61454
(- Case Report)
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- Co-Autor*innen der Med Uni Graz
- Beham-Schmid Christine
- Friesenbichler Jörg
- Holzer Lukas
- Leithner Andreas
- Liegl-Atzwanger Bernadette
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- Abstract:
- We present the case of a 62-year-old male patient with a three-month history of pain in the left shoulder. Magnetic resonance imaging of the left scapula showed an osteo-destructive lesion. H and E stained sections revealed a Langerhans cell sarcoma, and immunohistochemistry was performed additionally; CD68, CD163, CD14, fascin, HLA-DR, lysozyme, S100 CD1a and langerin showed a positive reaction, while CD20, CD30, CD34, CD31, pan-cytokeratin, AE/1AE3, SMA, desmin, EMA, ERG, INI-1, CD21, CD4, PLAP, MPO and CD117c were negative. We suggested palliative treatment with chemotherapy and radiation. The patient refused any treatment and died 2 weeks later.
- Find related publications in this database (using NLM MeSH Indexing)
- Biomarkers, Tumor - analysis
- Humans -
- Immunohistochemistry -
- Langerhans Cell Sarcoma - pathology
- Male -
- Middle Aged -
- Find related publications in this database (Keywords)
- Langerhans cell sarcoma
- histiocytic cell tumour
- diagnosis
- treatment
- histology