Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Borumandi, F; Higgins, JP; Buerger, H; Vasilyeva, A; Benlidayi, ME; Sencar, L; Gaggl, A.
Arterialized Venous Bone Flaps: An Experimental Investigation.
Sci Rep. 2016; 6(39):31970-31970
Doi: 10.1038/srep31970
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- Co-Autor*innen der Med Uni Graz
- Vasilyeva Anna
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- Abstract:
- In arterialized venous flaps (AVFs) the venous network is used to revascularize the flap. While the feasibility of AVFs in soft tissues has been reported there is no study on osseous AVFs. In this study we aim to assess the flap survival of osseous AVFs in a pig model. Medial femoral condyle flaps were elevated in 18 pigs. Three groups were created: AVF (n = 6), conventional arterial flap (cAF, n = 6) and bone graft (BG, n = 6). The AVFs were created by anastomosis of genicular artery with one vena comitans while leaving one efferent vein for drainage. After 6 months the specimens were harvested. The histology and histomorphometry of of the bone in cAF and AVF was significantly superior to bone grafts with a higher bone volume in AVFs (p = 0.01). This study demonstrates that osseous free flaps may be supported and survive using the technique of arterialization of the venous network. The concept of AVFs in osseous flaps may be feasible for revascularization of free flaps with an inadequate artery but well developed veins. Further experimental and clinical studies are needed to assess the feasibility of clinical use of arterialized venous bone flaps.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Arteriovenous Shunt, Surgical -
- Bone Transplantation -
- Bone and Bones - pathology
- Bone and Bones - surgery
- Graft Survival -
- Surgical Flaps - blood supply
- Swine -
- Veins - physiology
- Veins - surgery